Abstract

Gram-positive cocci are emerging causes of spontaneous bacterial peritonitis (SBP), especially in patients with healthcare-associated infections. We report the case of a 68-year-old man with hepatitis C virus and alcohol-related cirrhosis who developed SBP due to methicillin-resistant Staphylococcus aureus treated with daptomycin. We discuss the potential role of daptomycin in this setting with a review of the literature about the use of daptomycin in primary or secondary bacterial peritonitis.

Highlights

  • Policlinico Umberto I “Sapienza”, University of Rome, Italy nly Abstract o Gram-positive cocci are emerging causes of e spontaneous bacterial peritonitis (SBP), especially in patients with healthcare-associated s infections

  • We report the case of a 68-year-old u man with hepatitis C virus and alcohol-related l cirrhosis who developed spontaneous bacterial peritonitis (SBP) due to methiia cillin-resistant Staphylococcus aureus treated with daptomycin

  • Ceftriaxone therapy was replaced with meropenem (1 g IV BID; dose adjusted for creatinine clearance)

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Summary

Introduction

Policlinico Umberto I “Sapienza”, University of Rome, Italy nly Abstract o Gram-positive cocci are emerging causes of e spontaneous bacterial peritonitis (SBP), especially in patients with healthcare-associated s infections. Daptomycin 6 mg/kg/day was initiated, considering the high MIC of vancomycin and the concomitant presence of renal insufficiency and thrombocytopenia.

Results
Conclusion

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