Spontaneous arterial thrombosis associated with nephrotic syndrome: case report and review of the literature.

Abstract

Hypercoagulability is a recognized complication of the nephrotic syndrome which commonly affects the venous system. Arterial thrombosis is very rare. Multiple factors contribute to the predisposition to thromboembolism in this condition. This report deals with a case of femoral artery thrombosis which responded well to thrombectomy and a short course of anticoagulant therapy. In spite of several exacerbations of his disease, our patients had no recurrence of thrombosis. Review of the literature reveals high rates of limb loss and recurrence of thrombosis. We, therefore, feel that it is important to emphasize this rare entity in view of the associated morbidity.