Abstract
Advances in neuroscience continue to fuel a revolution in our fundamental understanding of the nature of drug abuse and addiction. The growing understanding that addiction is a brain disease that is expressed as a form of compulsive behavior is influencing the direction of basic research and revitalizing drug abuse prevention and treatment efforts. The application of powerful new scientific tools and emerging technologies is accelerating advances in neuroscience research, and affording a glimpse into the mechanisms underlying the psychoactive and addicting effects of drugs of abuse. In addition, new technologies are revealing the complex interrelationship among molecular, cellular, neurobiological, and behavioral systems, and how they are altered by drugs of abuse. National Institute on Drug Abuse (NIDA) sponsored research has supported many advances in our understanding of this disease. Indeed, NIDA’s mission is to lead the Nation in bringing the power of science to bear on drug abuse and addiction. This charge has two components. The first is the strategic support and conduct of research across a broad range of disciplines. The second is ensuring the rapid and effective dissemination of the research to improve significantly the prevention, treatment, and policy related to drug abuse and addiction. The mini-review papers published in this NIDA-sponsored special issue of TheScientificWorldJOURNAL on “Frontiers in Addiction Research” exemplify the depth, breadth, and sophistication of the research in the field, and fulfill NIDA’s mission to disseminate scientific knowledge rapidly and effectively. The mini-reviews in this special issue are written by speakers from the 2007 NIDA-supported satellite meeting, “Frontiers in Addiction Research”, held in conjunction with the annual meeting of the Society for Neuroscience (SfN), and from NIDA-supported symposia presented during the annual SfN meeting itself. The editorials in this issue, provided by symposia chairs, summarize the science and highlight research gaps and opportunities captured by the various symposia. The four symposia from the 2007 NIDA satellite meeting include:
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