Abstract

AbstractTwo cases of split hand and foot anomaly in male Macaca mulatta are described. Radiographs and dissection of the muscular anatomy of the first case showed that the muscular changes could be directly related to the osseous deformities. Comparison of the anatomy of case 1 with that of two other nonhuman primate cases on record suggests that two different developmental patterns and possibly two different genotypes may underlie the anatomical differences observed. The second case of the anomaly has been sent to the University of Washington Medical Lake Breeding Facility where it is hoped future pedigree data may provide information on some of the embryological and genetic questions raised by the existing materials.

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