Abstract
Background Diffuse myocardial fibrosis may be quantified with cardiovascular magnetic resonance (CMR) by calculating extra-cellular volume (ECV) from native and post-contrast T1 values. Previous studies have used either infusion or single bolus contrast administration. In clinical practice however split dose contrast injection is used as part of a stress/rest protocol in stress perfusion studies. The effects of using such an injection regime on ECV calculation is unknown. This study aimed to assess the effects of split dose versus single bolus contrast administration on ECV calculation.
Highlights
Split dose versus single bolus gadolinium administration in ecv calculation at 3 tesla cmr
Diffuse myocardial fibrosis may be quantified with cardiovascular magnetic resonance (CMR) by calculating extra-cellular volume (ECV) from native and post-contrast T1 values
In clinical practice split dose contrast injection is used as part of a stress/rest protocol in stress perfusion studies
Summary
Split dose versus single bolus gadolinium administration in ecv calculation at 3 tesla cmr. Adam K McDiarmid2*, David M Higgins, David A Broadbent, David P Ripley, Peter P Swoboda, Ananth Kidambi, Bara Erhayiem, Tarique A Musa, Laura E Dobson, Pankaj Garg, John P Greenwood, Sven Plein
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