Abstract
Abstract Recovery (chiefly repair of sublethal radiation injury) was compared for a range of euoxic and hypoxic normal and tumor cells and tissues. A wide spectrum of recovery potential was found, ranging from none for the testes to low for lymphocytes, bone marrow, and thymic tumors, intermediate for normal lung, breast tumors, and sarcomas, and marked for skin, gut, and esophagus. Severe hypoxia reduced or eliminated recovery, particularly when applied during or between radiation doses. These factors support the use of hyperfractionated radiation therapy in many tumor.
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