Abstract
The genome of eukaryotes is interspersed with sequences, known as introns, which are removed from the primary gene transcripts. The sequences that remain are known as exons, and they are spliced together as the introns are removed, forming the mRNA. The machinery responsible for splicing reactions is called the spliceosome. It is so intricate and dynamic that it is deservedly known as the most complex molecular machine in the cell.
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