Abstract
The therapeutic effects of splenectomy in 18 patients of acquired hemolytic anemia managed from 1982 to 2002 at Sher-iKashmir Institute of Medical Sciences, Srinagar (Jammu & Kashmir), India were studied. The mean age was 43 years (range 12-72 years). Male to female ratio was 1:3.5. the main preoperative finding was anemia in all patients. The mean Hb was 7.2 g% (range 5.2-9.0g%). None of these patients presented with thrombocytopenia or leucopenia. The response to splenectomy was excellent i.e., 76% showed complete response and 12% showed partial response. However, the morbidity (16%) and mortality (5.5%) observed was quite high. Overall 88% patients were benefited by the procedure. Thus, we conclude that splenectomy is an excellent treatment to improve hematological parameters in patients with acquired hemolytic anemia refractory to other types of therapy.
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