Abstract

Hodgkin’s disease (HD) remains one of the most baffling and poorly understood of the human lymphomas. The number of theories advanced to account for the aetiology of this disease are legendary, ranging from the early attempts to line it to tuberculosis (1), to more recent searches for a viral agent (2). As regards the nature of the neoplastic cell, the last two years have seen proposals that the HD cell is a macrophage (3,4), a T cell (5), a B cell (6) and a dendritic cell (7).

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