Abstract

The spirooxindole heterocyclic scaffold is found in many natural products and has been identified as an important bioactive agent. Over the past few decades, various spirooxindole-containing compounds have been reported to possess biological properties and hence found in the structure of many synthetic pharmaceuticals. This mini-review describes the most promising examples of this class of compounds possessing biological activity including anticancer, anti-inflammatory, and antimicrobial activities. The current review focuses on the biological activity of compounds containing the spirooxindole scaffold.

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