SPIROMETRIC FEATURES OF PATIENTS WITH EXCESSIVE DYNAMIC EXPIRATORY CENTRAL AIRWAY COLLAPSE

Abstract

PURPOSE: Excessive dynamic expiratory central airway collapse (EDAC) results from an exaggerated protrusion of the posterior membrane into the airway lumen causing a decrease in the cross-sectional area of more than 50%. This condition is accompanied by signs and symptoms that mimic asthma and COPD. Recent advances in diagnostic studies and the development of new multidimensional classification systems permitted the differentiation of this condition from tracheobronchomalacia based on the morphology of airway abnormalities. To date there are no studies evaluating spirometric testing and bronchodilator response in affected patients.