Abstract
We characterise the effects of ionic conductance and concentration changes on the meandering patterns and dynamics of re-entrant excitation in models of mammalian ventricular tissue. An increase in the spatial extent of spiral wave meander might lead to an increased likelihood of self-termination of the re-entrant excitation, since the probability of the spiral core meeting and annihilating at the in-excitable tissue boundaries is increased. Thus, the spiral-wave meandering behaviour and dynamics provides a potential target for antiarrhythmic drugs.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
