Spindle Cell Neoplasm

Abstract

Spindle neoplasm an uncommon variant of benign lipomatous tumor, occurs mostly in the posterior neck or the shoulder  It contains well circumscribed & no aggressive subcutaneous mass  Spindle cell neoplasm may be traced to epithelial, mesenchymal & odontogenic  Latin (AE1/AE3, K1), K1, K18, and EMA appear to be the most sensitive/reliable epithelial spindle cell neoplasms.  Spindle cell neoplasms can be benign or malignant. Under a microscope, the neoplasm is composed of adipocytes flat cells and long, thin spindle cells. In a spindle cell lipoma, the adipocytes are surrounded by spindle cells.  The diagnosis test includes immunohistochemistry and fluorescence in site hybridization (FISH) to confirm the diagnosis and to include other tumors that can look like a spindle cell lipoma. If a spindle cell neoplasm is large or uncomfortable, it can be removed.