Abstract
Hemangioendothelioma (HE) is a vascular malignancy which shows a borderline biological behavior. Spindle cell HE (SCHE) is a type of hemangioendothelioma, first described by Weiss and Enzinger in 1986. We present a case of 58-year-old male, who presented with fracture right femur. The biopsy showed necrotic bone with features of soft-tissue SCHE. Immunohistochemistry showed diffuse positivity of cluster of differentiation 31 in the tumor cells. Although SCHE has been pondered as a low-grade/borderline malignancy, few cases have been reported as locally aggressive and invasive behavior in the literature. The overall prognosis is excellent and no metastases from this locally aggressive tumor have been reported till date.
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