Abstract
Migraine subjects experience a derangement of the nociceptive system control as the disease progresses. The endocannabinoid system may modulate the nociceptive pathways. We evaluated the nociceptive spinal modulation together with anandamide (AEA) and palmitoylethanolamide (PEA) circulating levels in patients with episodic migraine exposed to nitroglycerin (NTG - 0.9 mg, sublingual).
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