Spinal block characteristics of intrathecal 1% 2chloroprocaine following addition of dexmedetomidine versus fentanyl in lower abdominal surgery: A prospective randomised controlled double blinded study

Abstract

The use of spinal anaesthesia for day care lower abdominal surgeries is limited due to its characteristics like delayed ambulation, urinary retention etc. The ultrashort acting 1% 2chloroprocaine (2CP) shows the properties of ideal local anaesthetic for short duration surgeries. The aim of this study was to compare the efficacy of two different adjuvants (fentanyl or dexmedetomidine) with intrathecal2CP for spinal block characteristics.A prospective randomised double blinded study was conducted on 126 patients scheduled for short duration lower abdominal surgeries under spinal anaesthesia. They were randomised into 3 groups. Group C received 40µg of 1% 2CP while group F received 2CP + 25µg fentanyl; and group D received 2 CP + 10µgdexmedetomidine. Tactile and engine bar qualities, prerequisite of post usable absence of pain, haemodynamics and sedation score were evaluated. The segment information, length of medical procedure, beginning of tangible square, an ideal opportunity to arrive at top tactile level were practically identical in every one of the three groups(P>0.05). Span of tactile & engine block & postoperative absence of pain was essentially delayed in bunch D versus bunch F & gathering C(P<0.001). Intrathecal addition of dexmedetomidine (10µg) & fentanyl (25µg) to 1%2CP brought about an essentially delayed tangible & engine bar with postoperative absence of pain. However, dexmedetomidine was viewed as a preferable adjuvant over fentanyl as far as drawn out length of absence of pain with insignificant secondary effects.