Spinal Anesthesia with 0.5% Hyperbaric Bupivacaine with Neostigmine for Prolong Anaesthesia

Abstract

Introduction: Pain is perhaps the most feared symptom of disease, which man is always trying to alleviate and conquer since ages. The relief of pain has been the fundamental aspect of the practice of anaesthesiology and remains one of the most important and pressing responsibilities of the anaesthesiologist. Presently, spinal anesthesia is a safe, convenient & economical form of regional anesthesia technique, & has gained widespread popularity in developing world. Objective: To compare the effectiveness spinal anesthesia with 0.5% hyperbaric bupivacaine with neostigmine for prolong anaesthesia. Materials and Methods: The present prospective study was undertaken Dept. of Anesthesiology, Department of Anesthesiology, Medical College for women and Hospital, Uttara, Dhaka, Bangladesh from January to June 2021. After obtaining local ethical committee approval & a written informed valid consent, a prospective study was conducted on 100 patients (Random sampling based on type of surgery) undergoing infra umbilical surgery under spinal anaesthesia. The patients were randomly divided into following two groups with 50 subjects in each group where group-A received Intrathecal Bupivacaine 0.5% (Hyperbaric) 3ml and 50µg of neostigmine (0.1ml) were group-B. Results: Out of total 100 parturient in the study, in comparison between group A age mean±SD 44.16±14.17 and group B 45.88±10.17 and weight (kg) mean±SD group A 70.88±6.52 and group B 68.28±8.99. No statistical difference was observed which was tested by applying unpaired t test (p>0.05). No statistical difference was observed which was tested by applying unpaired t test (p>0.05). Group A had 27 (54%) male patients and 23 (46%) female patients whereas Group B had 28 (56%) male patients and 22 (44%) female patients. The gender distribution in the two groups as per Fisher’s test were comparable and statistically not significant (p>0.05). Group A had 33 patients (66%) with Class I grading and 17 (34%) patients with Class II .....