Abstract
Polarised 3He gas has been used since 1996 to make in vivo lung NMR images of increasing quality. For the methodological studies performed by various groups so far, hyperpolarised (HP) gas is obtained by laser optical pumping. We present examples of HP gas MRI investigations with potential diagnostic applications. We report on our MRI work at low field (0.1 T), which could result in reduced requirements in equipment and 3He gas. The growing interest in 3He gas MRI should lead to the development of cost-efficient schemes to produce large amounts of HP gas and to efficiently recycle 3He. Cryogenic techniques have been proposed to polarise or compress 3He gas. Their potential interest is discussed considering recent technical developments.
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