Sphingosine 1-phosphate inhibits DNA synthesis induced by growth factors in cultured rat hepatocytes with activation of the small GTpase Rho via G protein-coupled receptor EDG5: Hitoshi Ikeda, Mikio Yanase, Yukiko Inoue, Tomoaki Tomiya, Masahiro Arai, Kazuaki Tejima, Kayo Nagashima, Department of Gastroenterology, University of Tokyo, Tokyo Japan; Hiroaki Satoh, Department of Diabetes & Metabolism, University of Tokyo, Tokyo Japan; Yutaka

Abstract

Sphingosine 1-phosphate inhibits DNA synthesis induced by growth factors in cultured rat hepatocytes with activation of the small GTpase Rho via G protein-coupled receptor EDG5: Hitoshi Ikeda, Mikio Yanase, Yukiko Inoue, Tomoaki Tomiya, Masahiro Arai, Kazuaki Tejima, Kayo Nagashima, Department of Gastroenterology, University of Tokyo, Tokyo Japan; Hiroaki Satoh, Department of Diabetes & Metabolism, University of Tokyo, Tokyo Japan; Yutaka