Abstract
Background: Anal carcinoma is a rare tumor, accounting for around 2–4% of all GI carcinomas. An increase in frequency has been described recently. The maximum age was 70 years. Simultaneous chemoradiotherapy(CRT) was able to establish itself as the standard therapy due to the potential for preservation of continence. Combined CRT with 5-fluorouracil (5-FU) and mitomycin-C (MMC) is currently the treatment of choice for all anal squamous cell carcinomas(SCC). The indication for abdominoperineal resection is today only as a
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