Abstract

BackgroundFungal sphenoid sinusitis mimicking as malignant tumor and invading the pituitary fossa is an uncommon entity. This report aims to highlight radiological salient features to help differentiate fungal lesion from malignant tumor in sphenoidal sinus mass lesions.Case presentationWe intend to report a case of middle-aged female who presented with gradual progressive diminution of vision since 3 years complicated with acute attack of unilateral headache and numbness. Computed tomography (CT) showed hyperdense lesion involving the sphenoid sinus extending into pituitary fossa and bilateral cavernous sinuses with smooth bony remodeling. Lesion appeared hypointense on T2-weighted and hyperintense on T1-weighted images on magnetic resonance imaging (MRI). Surgical excision of the lesion was done and pathological examination showed fungal hyphae and aspergillus fumigatus species on culture after 2 weeks of incubation. Post-operative CT revealed empty sinuses with surrounding bone remodeling.ConclusionCombination of T1 hyperintensity, T2 hypointensity, and hyperdense sinus is a strong predictor of fungal mass lesion involving sphenoid sinus.

Highlights

  • Fungal sphenoid sinusitis mimicking as malignant tumor and invading the pituitary fossa is an uncommon entity

  • Combination of T1 hyperintensity, T2 hypointensity, and hyperdense sinus is a strong predictor of fungal mass lesion involving sphenoid sinus

  • Acute fulminant aspergillus sinusitis occurs in immunocompromised hosts which can spread through vessels and nerves leading to vascular thrombosis or orbital nerve invasion leading to blindness

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Summary

Introduction

Fungal sphenoid sinusitis mimicking as malignant tumor and invading the pituitary fossa is an uncommon entity. This report aims to highlight radiological salient features to help differentiate fungal lesion from malignant tumor in sphenoidal sinus mass lesions. Case presentation: We intend to report a case of middle-aged female who presented with gradual progressive diminution of vision since 3 years complicated with acute attack of unilateral headache and numbness. Computed tomography (CT) showed hyperdense lesion involving the sphenoid sinus extending into pituitary fossa and bilateral cavernous sinuses with smooth bony remodeling. Case presentation A 45-year-old lady presented in the Department of Ophthalmology with bilateral gradual painless progressive diminution of vision (D.O.V) since 3 years in left eye and 1 year in right eye along with unilateral left sided headache and numbness of face for 15 days. Headache was diffuse in nature but more prominent in retro-orbital region on left side

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