Abstract

Paternal miRNAs, one of the important epigenetic factors, can be delivered to the oocyte during fertilization. It has been reported that sperm-borne miR-34c is important for the first cleavage division of mouse embryo. The objective of our study os to investigate whether the expression of miR-34c in human sperm is related with intracytoplasmic sperm injection (ICSI) outcomes, such as fertilization rate, early cleavage rate, good quality embryo rate, pregnancy rate and implantation rate.

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