Abstract
Challenges associated with habitual intake of alcohol including health, social, psychological and especially reproductive health needs urgent attention. This study aimed to determine the spermatotoxic effect of selected traditional alcoholic beverages in rats. A total of 30 normal male Spaque dawley strain albino rats weighing 180-220g, divided into 5 groups of 6 rats in each were administered with 10ml/kg p.o each of pito, goskolo and ogogoro, goskolo respectively and 0.5ml/kg normal saline for a period of 21 days. Sperm samples were harvested from the left caudal portion epididymis assayed for sperm motility, sperm morphology and sperm count after which histological examination was carried out on the testes. Results showed that active, sluggish and dead sperm cells were goskolo>pito>burukutu>control>ogogoro, ogogoro> burukutu> control>goskolo>pito and control>pito>ogogoro>burukutu>goskolo respectively. For morphology of sperm cells, it was goskolo>ogogoro>burukutu>control>pito (normal) and pito>control>burukutu> ogogoro> goskolo (abnormal). Also, that of sperm count was goskolo>ogogoro>pito>burukutu>control. Results further showed that ogogoro and goskolo caused significant negative effects on quantity and quality of sperm cells with alteration of histological parameters marked with altered secondary spermatogonia and spermatid. These effects were however mild with pito and burukutu. Traditional alcoholic beverages from North central Nigeria ‘pito’, 'burukutu', 'ogogoro', and goskolo' have negative on the quantity and quality of sperm cells with marked with infraction of spermatogonia of male albino rats. As a result of the spermatotoxic properties of these locally available and often ingested drinks by males predominantly in the reproductive age brackets will do well to avoid and or minimize its use as it leads to reprotoxicity.
Highlights
Challenges associated with habitual intake of alcohol including health, social, psychological and especially reproductive health needs urgent attention
For the sperm motility in terms of percentage active sperm cells, the highest percentage active sperm cell was observed in the shown by the ogogoro administered group (72%) when compared with Control (66.40%) while the least active was that of goskolo (42.4%)
There was significant difference for the group that were administered with goskolo 0.005 (p
Summary
Challenges associated with habitual intake of alcohol including health, social, psychological and especially reproductive health needs urgent attention. The unrecorded alcohol consumption such as the local brews: burukutu, pito, goskolo and ogorogo in Nigeria is said to have been estimated at 3.5 liters pure alcohol per capita for population of people older than 15 for the year after 1995 [2]. Studies have shown that for both men and women there is a sharp upward tick in alcohol consumption during adolescence, that peaks in early adulthood and plateaus at midlife and declines as they get into older ages [3]. It is clear that the fertility, reproductive stature age range fall within 15-49 years of age and it peaks within the 20-34 years in different urban settlements for women, with a little difference in rural areas where there is low education and other factors that make people marry at early age [5]. Studies have shown fertility increase within 30-40 years for men [6]
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