SPERMATOGENESIS FOLLOWING THE ADMINISTRATION OF ANDROGEN AND GONADOTROPIN IN A CASE OF EUNUCHOIDISM: COINCIDENTAL NEOPLASM DURING THERAPY

Abstract

THE phenomenon of spermatogenesis achieved after testosterone and gonadotropin therapy in the eunuchoid individual whose previously untreated case of relatively severe hypogonadism is reported herewith is noteworthy. While receiving treatment, the patient suddenly developed a malignant tumor. Neoplastic growth—intriguing at all times—merits special consideration when it occurs rapidly in the wake of endocrine therapy in humans, even if the element of chance must be weighed heavily in the theoretical evaluation of possible etiology.