Abstract

Introduction: Despite the importance of thyroid hormones in reproduction, there are only a few studies that focus on male infertility. The objective of this study was to evaluate semen parameters in patients with hypothyroidism or hyperthyroidism. Materials and methods: Totally, 28 patients with thyroid disorders were evaluated for the semen parameters. Serum TSH and T4 concentrations were measured by ELISA. Complete semen analyses were performed based on WHO. Results: Pathozoospermia was seen in 32.14% of our patients. Two hyperthyroid patients and seven hypothyroid patients suffered sperm defects. None of pathozoospermia patients showed an alone sperm defects. Sperm multiple anomalies were our main findings. Conclusion: It seems that sperm characterizes strongly were affected. Although, we have a limited sample size, but sperm multiple abnormalities made our interest findings.

Highlights

  • Despite the importance of thyroid hormones in reproduction, there are only a few studies that focus on male infertility

  • A total of 6 (21.42%) of 28 patients had considered as hyperthyroidism, which was identified in serum levels of TSH and T4

  • Our results showed that other participants (n= 22) may be in place Hypothyroidism for their TSH and T4 serum levels

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Summary

Introduction

Despite the importance of thyroid hormones in reproduction, there are only a few studies that focus on male infertility. The objective of this study was to evaluate semen parameters in patients with hypothyroidism or hyperthyroidism. Materials and methods: Totally, 28 patients with thyroid disorders were evaluated for the semen parameters. Two hyperthyroid patients and seven hypothyroid patients suffered sperm defects. None of pathozoospermia patients showed an alone sperm defects. Sperm multiple anomalies were our main findings. We have a limited sample size, but sperm multiple abnormalities made our interest findings. In approximately 15 % of cases, the etiology remains unclear [4]. This complex procedure is influenced by varying factors such as hormones. It is wellestablished that endocrine system has an important physiological role in maintaining and regulation of sexual development and reproductive function [5,6,7]

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