Speed-of-sound estimation in ultrasound propagation medium by considering size of target scatterer.

Abstract

Accurate speed-of-sound (SoS) estimation in an ultrasound propagation medium improves imaging quality and contributes to better diagnosis of diseases. In conventional time-delay-based SoS estimation approaches studied by several groups, a received wave is assumed to be scattered from an ideal point scatterer. In these approaches, the SoS is overestimated when the target scatterer has a non-negligible size. In this paper, we propose the SoS estimation method that considers target size. In the proposed method, the error ratio of the estimated SoS using the conventional time-delay-based approach is determined from measurable parameters using the geometric relationship between the received elements and target. Subsequently, the SoS erroneously estimated using conventional estimation, assuming the ideal point scatterer as a target, is corrected by the determined estimation error ratio. To validate the proposed method, the SoS in water was estimated for several wire sizes. The SoS in the water was overestimated using the conventional SoS estimation method, with a maximum positive error of 38m/s. The proposed method corrected the SoS estimates, and the errors were suppressed to within 6m/s, irrespective of the wire diameter. The present results demonstrate that the proposed method can estimate the SoS by considering the target size without using information on the true SoS, true target depth, and true target size, which is applicable to in vivo measurements.