Speed of normalization of right ventricular volume overload after transcatheter closure of atrial septal defect in children and adults

Abstract

Right ventricular (RV) volume overload occurs in patients with significant atrial septal defect (ASD) shunt, which can impair left ventricular (LV) filling and ejection fraction. 1 Louie E.K Lin S.S Reynertson S.I Brundage B.H Levitsky S Rich S Pressure and volume loading of the right ventricle have opposite effects on left ventricular ejection fraction. Circulation. 1995; 92: 819-824 Crossref PubMed Scopus (149) Google Scholar RV dilation and abnormal ventricular septal motion are characteristic echocardiographic features of RV volume overload. Transcatheter closure of secundum ASD was first attempted >25 years ago, and it is being increasingly used in recent years with promising closure results. 2 Rome J.J Keane J.F Perry S.B Spevak P.J Lock J.E Double-umbrella closure of atrial septal defects initial clinical applications. Circulation. 1990; 82: 751-758 Crossref PubMed Scopus (278) Google Scholar , 3 Das G.S Voss G Jarvis G Wyche K Gunther R Wilson R.F Experimental atrial septal defect closure with a new, transcatheter, self-centering device. Circulation. 1993; 88: 1754-1764 Crossref PubMed Scopus (204) Google Scholar , 4 Prieto L.R Foreman C.K Cheatham J.P Latson L.A Intermediate-term outcome of transcatheter secundum atrial septal defect closure using the Bard Clamshell Septal Umbrella. Am J Cardiol. 1996; 78: 1310-1312 Abstract Full Text PDF PubMed Scopus (78) Google Scholar , 5 Rao P.S Berger F Rey C Haddad J Meier B Walsh K.P Chandar J.S Lloyd T.R de Lezo J.S Zamora R Sideris E.B Results of transvenous occlusion of secundum atrial septal defects with the fourth generation buttoned device comparison with first, second and third generation devices. International Buttoned Device Trial Group. J Am Coll Cardiol. 2000; 36: 583-592 Abstract Full Text Full Text PDF PubMed Scopus (83) Google Scholar , 6 Masura J Gavora P Formanek A Hijazi Z.M Transcatheter closure of secundum atrial septal defects using the new self-centering Amplatzer septal occluder initial human experience. Cathet Cardiovasc Diagn. 1997; 42: 388-393 Crossref PubMed Scopus (406) Google Scholar , 7 Thanopoulos B.D Laskari C.V Tsaousis G.S Zarayelyan A Vekiou A Papadopoulos G.S Closure of atrial septal defects with the Amplatzer occlusion device preliminary results. J Am Coll Cardiol. 1998; 31: 1110-1116 Abstract Full Text Full Text PDF PubMed Scopus (258) Google Scholar This study evaluates the change in RV volume overload after transcatheter closure of ASD by echocardiography and assesses the possible influencing factors.