Speculated Mechanism of Gas Plasma Sterilization

Hideharu Shintani

doi:10.4172/2150-3494.1000e109

Abstract

As already published by Shintani et al, gas plasma sterilization is the alternative sterilization procedures to the existing sterilization procedures due to applicable to the several sensitive healthcare products and attainable both sterility assurance level (SAL) of 10-6 and material/functional compatibility, which authorities and GMP (good manufacturing practice) are required. In addition there was progress in the field of plasma-based sterilization, there are still some questions. The aim of this editorial is to mention briefly some of un-resolved sterilization mechanisms as well as to draw further perspectives of sterilization technique.

Highlights

As already published by Shintani et al, gas plasma sterilization is the alternative sterilization procedures to the existing sterilization procedures due to applicable to the several sensitive healthcare products and attainable both sterility assurance level (SAL) of 10-6 and material/functional compatibility, which authorities and GMP are required
In addition there was progress in the field of plasma-based sterilization, there are still some questions. The aim of this editorial is to mention briefly some of un-resolved sterilization mechanisms as well as to draw further perspectives of sterilization technique
Nitric monooxide radical detected by us [1] combines with superoxide anion and produce peroxynitrite anion on the biological indicator spores or bioburden to sterilize them

Summary

Introduction

As already published by Shintani et al, gas plasma sterilization is the alternative sterilization procedures to the existing sterilization procedures due to applicable to the several sensitive healthcare products and attainable both sterility assurance level (SAL) of 10-6 and material/functional compatibility, which authorities and GMP (good manufacturing practice) are required. Hideharu Shintani* Chuo University, Department of Science and Engineering, 1-13-27, Kasuga Bunkyo, 112-0003, Tokyo, Japan The atmospheric and low-pressure gas plasma can be used to sterilize bioburden in the surfaces.

Results

Conclusion