Abstract
Dengue is a vector transmitted viral infection; tropical and subtropical countries see outbreaks of dengue each year. There is a paucity of literature on effects of dengue infection on pregnancy outcome and this prompted us to undertake a study for better understanding of pregnancy implications with dengue infection. Pregnant women admitted during the seasonal outbreak of dengue between September 2015 and October 2015 were studied and maternal and fetal outcomes in sixteen NS1Ag positive women were analysed. Out of sixteen women diagnosed with dengue fever, three had dengue shock syndrome (DSS) and eight had dengue haemorrhagic fever (DHF). The most common obstetric complication seen in 43% of the cases was oligohydramnios. Bleeding manifestations occurred in seven women and there were three maternal deaths. Perinatal complications included three intrauterine deaths, six nursery admissions, and one neonatal death. Thus dengue infection was associated with high maternal and perinatal mortality. In view of poor obstetric outcomes, this viral infection warrants early admission and prompt management.
Highlights
Out of 16 cases 13 presented in third trimester and two in second trimester and one was referred after LSCS was done in another hospital
She presented with large rectus sheath hematoma following caesarean section needing surgical exploration and drainage
Platelet count less than 30,000/mm3 was seen in dengue shock syndrome with increased risk of bleeding manifestations
Summary
It is caused by viruses of the genus Flavivirus, family Flaviviridae, and Group IV ssRNA. Dengue is transmitted to humans by the mosquito Aedes aegypti and is one of the most rapidly spreading viral infections. There has been a 30-fold increase in its incidence in the last 50 years coupled to increasing migration from rural to urban areas. 50 million people acquire dengue infection worldwide [1]. Dengue remains a major health concern for Southeast Asian countries with cyclic epidemics. In India multiple viral serotypes are circulating and some regions have case fatality rates of 3– 5% in general population, which is much higher than other Southeast Asian regions (1%) [2]
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