Abstract

Liver disease affects nearly 3% of pregnancies. It is a challenging topic for obstetricians as it can be fatal for both, the mother and the fetus. They carry a high mortality rate reaching 25%. Sex-specific effect on the expression of pregnancy-related liver diseases is largely unknown. We present several cases of familial pregnancy-related liver diseases that were expressed solely when the mothers had male fetuses, ending with deleterious outcomes. Liver disease was not expressed when they had female fetuses. These cases provide a novel insight into the diversity of pregnancy-related liver disease complications expression among sex.

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