Abstract
The significance of abnormal liver function tests in the absence of diagnostic serology is unclear. The aim of this prospective study is to report liver biopsy findings in a large group of patients with unexplained abnormal liver biochemistry and correlate them with the clinical features to assess the severity of these diseases. Percutaneous liver biopsy is a relatively safe and accurate method of diagnosing liver disease and should be considered in such cases. A total of 63 liver biopsies were studied for a period of 18 months from june 2012 to december 2013, of which, 34.92% (n=22) hepatic tumors, 20.63.%(13) glycogen storage disorders, 4.7% (n=03) cirrhosis, 4.7% (n=03) fatty liver and 4.7% (n=3) viral hepatitis, 4.7%(3) Non alcoholic steato hepatitis were seen. Further, 01.58% case (n=1) each of extra hepatic biliary atresia, amyloidosis, miliary tuberculosis, liver abscess, and liver cell dysplasia were also observed. Liver biopsy was non specific in 6.34% (n=4) and inadequate in 11.11% (n=7) cases. The role of histopathological examination of liver biopsy is highlighted in this paper.
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