Abstract

Background: The spectrum and incidence of congenital heart diseases amongst African population are not well defined in literature. There is the need to further elucidate the spectrum and epidemiology of congenital heart diseases amongst African. Aim: This study was conducted to highlight the spectrum and occurrence of congenital heart diseases in an African population. Methodology: All paediatric patients who were autopsied over a 98-month period were checked for occurrence of congenital heart diseases. Attempts were made to ascertain the primary disease and causes of death. We noted their bio-data, ages, sexes and causes of death. The results were analysed with SPSS version 17. The results formed the basis for discussion and recommendations. Results: There were 135 cardiac related deaths and 36 of them were in paediatric age brackets. The mean age was 4.7 + 1.08 months with a standard deviation of 6.27. M:F ratio was 1:1.1. The commonest anomaly was ventricular septal defect. There was a weak association with other congenital anomalies. The commonest cause of death was bronchopneumonia. Discussion and Recommendation: The disease pattern showed reasonable similarity with reports from other parts of the world. However, there is need for development of capacity for prenatal diagnosis of congenital heart diseases in Africa. This will widen the net of diagnosis and improve accuracy of incidence studies in Africa.

Highlights

  • Paediatric cardiac diseases are either congenital or acquired and they exhibit spectacular spectrum

  • It is common knowledge that some children with congenitally malformed hearts survive into adulthood: this is the same pattern with some acquired heart diseases

  • This research is a necropsy study of congenital heart diseases (CHD) patients

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Summary

INTRODUCTION

Paediatric cardiac diseases are either congenital or acquired and they exhibit spectacular spectrum. It is common knowledge that some children with congenitally malformed hearts survive into adulthood: this is the same pattern with some acquired heart diseases. Earlier reports have shown that little was known about the incidence and types of congenital heart diseases (CHD) in African children. A number of studies have attempted to define associations between specific cardiac defects and non-cardiac malformations [6,7] Among these associations, the well established ones are the association between Down Syndrome and endocardial cushion defects or ventricular septal defects (VSD), that between agenesis of spleen and conotruncal anomalies and between limb reductions and septal defects in OPEN ACCESS. This research was conducted to further unravel the pattern of heart diseases in children as found in autopsy studies

PATIENTS AND METHODS
RESULTS
Age and Sex Distribution of Cases
Primary Diseases and Sex Distribution
Other Anomalies
Causes of Death
DISCUSSION
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