Abstract
Objective:To find out frequency of various complications in children admitted with Enteric Fever at a tertiary care hospital.Methods:This was prospective cross sectional study, carried out in the Pediatric Medicine department of The Children’s Hospital Lahore from Dec 2014 to March 2017. Children of both genders with age range of 6 months to 16 years diagnosed as enteric fever on the basis of clinical features and positive Typhidot, or blood culture were included in the study. All 180 patients were scrutinized for all possible complications. Where ever required and feasible appropriate and relevant investigations were done to document complications. Data was analyzed by SPSS version 20.Results:Mean age of children was 7.2±3.38, majority 94 (52.2%) were 5-10 years old. Out of 180 patients, complications were noted in 58 (32.2%). Neurological complications 30.7% encompassed maximum complications followed by hepatobiliary 24.61%, abdominal 16.92% hematological 9.23%, bone and joints 7.69%, respiratory system 6.1% and cardiovascular system 4.41%. Mortality rate was 1.6%. Thrombocytopenia and leucopenia were significantly associated with complications with p value of 0.002 and 0.003 respectively.Conclusion:Enteric fever is causing our children to suffer by its numerous perplexing and fatal complications. The most vulnerable age for enteric fever and its complication is 5-10 years. To combat these issues large scale vaccination remains promising option at least in most susceptible age group.
Highlights
Even in 21st century heavy burden of Salmonella infections is still hovering around developing world and poses a continuous threat for health care providers
Pakistan is one of those five countries which have been declared endemic for Enteric fever with high burden.[3]
Nonprobability convenience sampling method was used. Children of both gender with age range of 6 months to 16 years who were diagnosed as enteric fever on the basis of clinical features including fever, vomiting, abdominal pain, diarrhea, malaise and laboratory criteria including Complete blood count and positive Typhi-dot or positive blood or stool culture, were included in the study after informed consent
Summary
Even in 21st century heavy burden of Salmonella infections is still hovering around developing world and poses a continuous threat for health care providers.
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