Abstract
Diabetic ulceration is a multi-factorial problem which is responsible for considerable morbidity threatening the health care system. By knowing the clinical profile and bio-burden on diabetic ulcer, it is highly beneficial for health treatment. The purpose of the present study was to evaluate the diversity of major bacterial etiology in diabetic ulcer patients. The different samples like pus, swab, and infected tissues were collected from diabetic ulcer patients aseptically and samples were transported through cold chain to the laboratory. The samples were cultured in nutrient agar, mannitol salt agar, macConkey agar and blood agar. Suspected colonies were biochemically confirmed for the isolation of Staphylococcus aureus, Pseudomonas aeruginosa, E.coli and Klebsiella spp. In total 150 diabetic ulcer patients suffering from diabetic foot ulcers, gangrene, burn cases and accidental ulcer cases were analyzed. However, most of the patients developed mono-microbial infection; S.aureus was the most prevalent microbe in diabetic ulcer cases, which were positive for nucA gene.
Highlights
Diabetic ulceration is a multi-factorial problem which is responsible for considerable morbidity threatening the health care system
The purpose of the present study was to evaluate the diversity of major bacterial etiology in diabetic ulcer patients
In total 150 diabetic ulcer patients suffering from diabetic foot ulcers, gangrene, burn cases and accidental ulcer cases were analyzed
Summary
Diabetic ulceration is a multi-factorial problem which is responsible for considerable morbidity threatening the health care system. Most of the patients developed mono-microbial infection; S.aureus was the most prevalent microbe in diabetic ulcer cases, which were positive for nucA gene. Diabetes is a major health issue that patients with different grades of wounds/ulcers has reached alarming levels with nearly half a and gangrene after obtaining written informed billion people living with diabetes worldwide. 463 million adults are living with Data collection diabetes and by 2045, this will rise to 700 million[1]. The proportion of people with type 2 diabetes data [age, marital status, literacy status, is increasing in most countries. Due to increased glucose levels and suppressed were collected from patients with diabetes using immune response as well as the neuropathy standardized questionnaires
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