Abstract

The effects of LSD, mescaline, harmine, phencyclidine, bufotenine, bulbocapnine and Brom-LSD on the resting EEG of multiple brain structures have been studied by spectral analysis methods. All the hallucinogenic compounds tested produced changes in the electrical activity of the amygdaloid complex. Alterations in other structures were also noted but appeared to be drug-specific. It is proposed that the limbic system, especially the amygdaloid complex, is an important site of action of hallucinogens.

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