Abstract
Seven types of complexes were obtained when penicillin G potassium (pin) was reacted with transition and non-transition metal ions in methanol/distilled water mixed solvent. Magnetic susceptibilities and ESR spectra (CuII complex) of powdered samples indicated that the monomeric form of the complexes in the solid state, and the paramagnetic nature of the CuII, NiII, MnII, CrIII, CoII, and FeIII complexes is attributable to the octahedral ligitional behavior of the potassium G penicillinate ligand. The antibacterial activity of the metal complexes were tested against some kind of bacteria and fungi strains and compared with penicillin G potassium activity. The possible mechanism of antibacterial action is discussed.
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