Spectroscopic and Thermal Investigation of Silver Nanoparticle Dispersed Biopolymer Matrix Bovine Serum Albumin: A Promising Antimicrobial Agent against the Pathogenic Bacterial Strains

Abstract

The present work describes the synthesis of the polypeptide coated silver nanoparticles by the excellent combination of the macromolecule bovine serum albumin (BSA) and nanosized silver particles (AgNPs). The product was characterised by spectroscopic, microscopic and X-ray diffraction analyses. The thermal characteristics were studied by TG-DTG and DSC measurements. The developed system was evaluated for its antibacterial property by disc diffusion method against the selected pathogenic gram positive and gram negative bacterial strains Streptococcus haemolyticus (+ve), Corynebacterium diphtheriae (+ve), Klebsiella ornithinolytica (-ve) and Salmonella paratyphi (-ve). The study revealed that the AgNP-BSA aggregates displayed appreciable thermal stability and better antimicrobial efficacy and is anticipated to be a promising material for antimicrobial applications.