Abstract
Fullerene (C60) is enhanced with pyrrolidine group to produce fulleropyrrolidine which is considered as one of the most important derivatives of fullerene. Fulleropyrrolidine is further modified in order to enhance its solubility which in turn could enhance its biological applications. Accordingly this work is dedicated to modify fulleropyrrolidine carbodithioic acid as NO2 group introduced at meta position. Quantitative structure-activity relationship models (QSAR) was utilized to evaluate the biological activates of the investigated compounds through some descriptors. Later on chalcogenide could be subtitled in order to form three derivative groups. The QSAR descriptors were compared with the QSAR of the parent compound. Results indicate that, NO2 group enhances the biological activity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callSimilar Papers
More From: The Open Spectroscopy Journal
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
