Abstract
It is shown that the treatment of chloroform solutions of drugs of the nitroimidazole series (NIm) with crystalline copper(II) acetate gives colored chloroform-soluble adducts of the general formula [Cu(CH3COO)2NIm]2, which can be used as analytical forms in the spectrophotometry determination of metronidazole and tinidazole. The respective analytical methods are developed and certified.
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