Abstract
The chromaticity coordinates and brightness of nearly 50 pharmaceutical colorants have been determined. The coordinates were calculated by a weighted ordinate method from the spectrophotometric reflectance curve of tablets prepared using the colorant. The use of the coordinates and the reflectance spectra in selecting colorants to match a color is explained. The modified Kubelka-Munk equation is used to calculate the concentration of colorant required for the match. Several examples are given which demonstrate how to match the color of a tablet to another tablet, to a color chip, or to other colored material. The method can be adapted to other nontransparent dosage forms such as ointments.
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