Abstract
A simple and sensitive spectrophotometric method has been described for the assay of Flucloxacillin either in pure form or in pharmaceutical solid dosage form. Absorption maxima of Flucloxacillin in methanol were found to be at 220 nm. Beer's law is obeyed in the range 5-70 μg/mL. Result of percentage recovery and placebo interference shows that the method was not affected by the presence of common excipients. The percentages assay of Flucloxacillin in tablet was more than 99%. The method was validated by determining its sensitivity, accuracy and precision which proves suitability of the developed method for the routine estimation of Flucloxacillin in bulk and solid dosage form.
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