Abstract
Abstract The roots and leaves of Cochlospermum planchonii and C. tinctorium are widely used in Burkina Faso as medication for malaria treatment. The cochloxanthins, carotenoids, are - at least partially - responsible for the antimalarial activity of Cochlospermum spp.. Because of large variation of cochloxanthin contents in rhizomes and leaves of Cochlospermum spp., the available products are not always reliable. The gold standard method for the quantification of cochloxanthins is HPLC. However, HPLC is expensive, time consuming, and needs experienced personnel. Therefore, for quick analysis of Cochlospermum roots in local pharmacies and companies, we developed a spectrophotometric method that is inexpensive, fast, simple and robust. In our study, we produced ethanolic extracts of market samples of roots of Cochlospermum sp. from Burkina Faso and analysed them in parallel by HPLC and spectrophotometry. The two methods correlated well with an R2 > 0.95 (P
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