Abstract
Central serous chorioretinopathy (CSC) typically affects young and middle-aged males and is characterized by serous retinal detachment at the macula secondary to increased permeability of choroidal vessels and a barrier defect in the retinal pigment epithelium (RPE) Spectral-domain optical coherence tomography (OCT) offers a new approach to diagnose, prognosticate, and monitor the clinical course of the disease and its response to therapy Morphologic alterations in the RPE, detached retina, and subretinal space around the fluorescein leakage sites can be observed in acute CSC Three-dimensional (3D) OCT imaging delineates the microstructural changes that occur within the photoreceptor layers and demonstrates the spatial relationship between the laterally spreading or scattering microstructures and the fovea in the eyes with CSC. Primarily, the outer segment layer is altered in CSC Visual prognosis in patients with CSC can be linked to retinal morphological changes by OCT Presence of correlation between foveal thickness and visual acuity has been observed Topographic changes in CSC can be very elegantly visualized and documented with 3D-reconstruction.
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