Abstract
In a series of structurally related cationic Eu(III) triamide complexes, the analysis of variations in emission lifetime and spectral signature as a function of probe environment has elucidated the nature of changes to probe speciation. The cationic complexes exhibit an intrinsic tendency to localise in cellular nucleoli or the lysosomes, providing key information in the design and evaluation of related targeted probes. Each of the three complexes studied possesses a coordinated water molecule in aqueous media, that is absent in organic solvents or is displaced by the addition of protein. The complex observed in cellulo is probably a protein-bound Eu complex.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.