Abstract
BackgroundTo report the rate of cystoid macular oedema (CMO) as detected by spectral-domain optical coherence tomography (SD-OCT) after intraoperative complication during phacoemulsification. The secondary objectives include comparing mean macular thickness and best-corrected visual acuity (BCVA) between those who developed postoperative CMO against those who did not.MethodsThis is a prospective cohort study conducted in a tertiary hospital between July 2009 and June 2010. Serial SD-OCT and BCVA were performed at baseline, 1 week, 6 weeks and 16 weeks postoperatively.ResultsSingle eyes from 47 subjects were analyzed; of these 16 (34%) eyes developed CMO. In the CMO group, mean macular thickness (±SD) increased sharply by 56 μm from 273 ± 24 μm at baseline to 329 ± 31 μm at 16 weeks; whereas in the non-CMO group, macular thickness showed a slight increase of 14 μm from 259 ± 21 μm to 272 ± 20 μm. In the CMO group, mean BCVA (in logarithm of minimum angle of resolution) improved modestly from 0.92 ± 0.66 to 0.66 ± 0.41 at week 16; while in the non-CMO group, mean BCVA improved markedly from 0.98 ± 0.59 to 0.21 ± 0.13. The two groups differed significantly in mean macular thickness (p < 0.001) and mean BCVA (p < 0.001) at 16 weeks.ConclusionAs detection rate of CMO is high, postoperative OCT monitoring for patients with intraoperative complications allows earlier diagnosis and treatment.
Highlights
To report the rate of cystoid macular oedema (CMO) as detected by spectral-domain optical coherence tomography (SD-OCT) after intraoperative complication during phacoemulsification
Clinical and clinically-significant CMO are terms used for patients with angiographic evidence of CMO accompanied by a decrease in best-corrected visual acuity (BCVA) [2]
Jittpoonkuson et al reported that OCT is more sensitive than fluorescein angiography (FA) in detecting CMO associated with retinal vein occlusion, age-related macular degeneration and diabetic retinopathy
Summary
To report the rate of cystoid macular oedema (CMO) as detected by spectral-domain optical coherence tomography (SD-OCT) after intraoperative complication during phacoemulsification. Clinical and clinically-significant CMO are terms used for patients with angiographic evidence of CMO accompanied by a decrease in best-corrected visual acuity (BCVA) [2] For cataract surgery, this is usually taken as Traditionally, fluorescein angiography (FA) is used to confirm the presence of perifoveal leakage. Jittpoonkuson et al reported that OCT is more sensitive than FA in detecting CMO associated with retinal vein occlusion, age-related macular degeneration and diabetic retinopathy. They found that CMO was missed by FA in 18.5%, 33.33% and 33.33% of these cases respectively [5]
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