Abstract
Abstract Purpose: We have realized a 150 fold improvement of the sensitivity over conventional time domain OCT technology allowing video rate in vivo retinal imagingwithout compromising image quality. Methods: Two different but similar technologies (SD‐OCT and OFDI) provide high speed imaging at a wavelength of 850 nm and 1050 nm, respectively. An overview of the latest system developments will be presented. Data processing techniques to extract and quantify features such as retinal nerve fiber layer thickness, drusen volume, CNV size and volume, and subretinal fluid volume will be presented for a number of glaucoma and AMD patients. Results: Ultra‐high‐resolution video rate SD‐OCT at 850 nm and OFDI at 1050 nm offers many advantages in retinal imaging, maintaining high signal to noise while operating at a safe ocular exposure level. Conclusions: The unprecedented speed eliminates motion artifacts and the need to re‐align A‐lines, enabling accurate 3‐D mapping of the retinal topography, and provides a shift from two‐dimensional imaging to three‐dimensional screening of large retinal volumes.
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