Spectral and magnetic properties and bio-activity of copper(II) clofibriates: Part I. Crystal and molecular structure of trans-Cu(clofibriate) 2(nicotinamide) 2

Abstract

New copper(II) clofibriate (clof) Cu(clof) 2 and its compounds of composition Cu(clof) 2L 2 (where L=nicotinamide (na) or ronicol (ron)) and Cu(clof) 2–caffeine are reported. The characterizations were based on elemental analysis, electronic and EPR spectra, and magnetic susceptibility measurements over the temperature range 4.5–300 K. The crystal and molecular structure of Cu(clof) 2(na) 2 has been determined. The copper(II) atom is bonded in a trans square-planar arrangement by two N atoms of two nicotinamide molecules and one carboxylate oxygen atom from each of two clofibriate anions. The remaining two carboxylate oxygen atoms of the anions at the axial positions completed a tetragonal-bipyramidal geometry. On the basis of spectral and magnetic properties structures of the compounds were proposed. The antimicrobial effects have been tested on various strains of bacteria, yeasts and filamentous fungi.