Abstract

Spectral analyses of 1% water extracts of fresh and dry Hypericum perforatum L. and 1% dry H. perforatum with colloidal nano silver (NSPs) 30 ppm were conducted. The nano silver is standardised and patented by the Swiss company Evodrop. Non-equliblrium energy spectrum (NES) and Differential non-equliblrium energy spectrum (DNES) methods were used for the spectral analysis. A comparative analysis of 1% extracts of fresh and dry H. perforatum was performed in order to determine the local extremums for effects of nerve tissue conductivity at (-0.1112) eV, anti-inflammatory (-0.1212) eV, anti-tumor effects (-0.1387) eV. The results showed stimulating effect on the nervous system and improvement of nerve conduction (local extremums E=-0.1112 eV)(?=11.15 ?m) (?=897 cm-1), as well as anti-inflammatory effect (E = -0.1212 eV)( ?=10.23 ?m) (?=978 cm-1) and inhibition of development of tumor cells at a molecular level (E=-0.1387 eV) (?=8.95 ?m) (?=1117 cm-1). It was found that clusters of 16 and 15 water molecules are formed in the water herbal extracts of fresh H. perforatum and of dry H. perforatum with AgNPs 30 ppm. The fresh plant showed better results then the dry one. The addition of colloidal nano silver 30 ppm led to better results of the drug.

Highlights

  • The application of herbs by doctors and pharmacists is a widespread practice worldwide, including in Bulgaria, which is a part of the national culture

  • John's wort), is a herbaceous perennial plant which grows in Europe, West Asia and North Africa. This herb is grown in South Africa, Australia, New Zealand, India and South America and it is used as a medicinal plant there

  • The Differential non-equliblrium energy spectrum (DNES) was determined in the range between -0.08 and 0.1387 eV or = 8.9–13.8 μm by an especially created computer program

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Summary

Introduction

The application of herbs by doctors and pharmacists is a widespread practice worldwide, including in Bulgaria, which is a part of the national culture. (St. John's wort), is a herbaceous perennial plant which grows in Europe, West Asia and North Africa. John's wort), is a herbaceous perennial plant which grows in Europe, West Asia and North Africa This herb is grown in South Africa, Australia, New Zealand, India and South America and it is used as a medicinal plant there. In Bulgaria, it grows all over the country in the lowlands - on grassy places and along roads [1]. St. John's wort is among the most commonly used herb. John's wort is among the most commonly used herb It is applied mainly as a means of treating a number of gastrointestinal diseases (gastric and duodenal ulcers with hyperacidity, acute and chronic gastritis, enterocolitis, indigestion, diarrhea, stomatitis, periodontitis, gingivitis, pharyngitis, etc.) [2].

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