Abstract
Nuclear medicine plays an important role in functional imaging of the adrenal glands. The introduction of SPECT/CT imaging has improved anatomic localization, offering better resolution and higher accuracy to this imaging method. Radiopharmaceuticals used in clinical practice for the visualization of the adrenal cortex and medulla permit the diagnosis of hormonally active or malignant tumors. Radiolabeled cholesterol analogue scintigraphy can discriminate benign from malignant adrenal cortex tumor. I-123 MIBG scintigraphy is considered the modality of choice in malignant pheochromocytoma. Futhermore, in patients with neuroblastoma as well as in metastatic pheochromocytoma MIBG scintigraphy can be used in the follow-up of the disease, in monitoring treatment response, and for the selection of the patients who can be treated with I-131 MIBG. Somatostatin analogs such as In-111 octreotide are the gold standard imaging method in neuroendocrine tumors.
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