SPECIFICS OF ANTIBODY GENESIS IN NOVOSIBIRSK BREED SM-1 PIGS IN THE PROCESS OF PHYLOGENESIS

Abstract

The article presents data reflecting the features of the synthesis of IgM and IgG in pigs of the SM-1 breed of Novosibirsk selection in phylogenesis. The studies were conducted on pigs on the 30th, 60th, 90th and 240th days of life in 1990, 1996 and 2006. birth. Each group of animals included 66 animals. Groups of animals were formed according to the method of analogues, taking into account age, body weight, sex and health. Pigs were bled from the cranial vena cava. The concentration of IgM and IgG in the blood serum of animals was determined by simple radial immunodiffusion. The study results showed that pigs born in 1990 differ from their peers born in 1996 and 2006 in statistically significant high levels of IgM at 30, 60, and 240 days of age and increased activity of IgG synthesis at three months of age. So, at 30 days of age, piglets born in 1990 exceeded the IgM content in the blood serum of sucklings born in 1996 by 15.5% (P<0.001) and piglets born in 2006 - by 20.0% (P<0.001). On the 60th day of life, the differences between pigs born in 1990 and 1996 and between 1990 and 2006 were, respectively, 26.2 (P<0.01) and 32.5% (P<0.01). In pigs on the 240th day of life, born in 1990, the concentration of IgM in the blood serum was 44.6% (P<0.001) higher than in pigs born in 1996 and 48.0% (P<0.001) higher than in pigs 2006 year of birth. At two months, piglets born in 1990 were inferior in IgG level to piglets born in 1996 by 24.4% and too young animals born in 2006 by 24.7% (P<0.01). A month after weaning, pigs born in 1990 demonstrated the best rehabilitation qualities of the immune system. As a result, piglets born in 1990 were ahead of their counterparts in 1996 and 2006. births by 26.1% (P<0.001) and 26.0% (P<0.001), respectively. Pigs 1996 and 2006 birth throughout the study showed a stable level of antibody genesis.